Elabscience

Recombinant Mouse TNF-alpha/TNFA Protein (aa 89-235)(Active)

Product Code:
 
PKSM041176
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041176-10ug10ug£180.00
Quantity:
PKSM041176-50ug50ug£378.00
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Further Information

Abbreviation:
TNF-alpha;TNFA
Accession:
P06804
Activity:
Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 2-8 pg/ml.
Background:
Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.
Calculated MW:
16.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
14 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asp89-Leu235
Target Synonym:
Tumor Necrosis Factor;Cachectin;TNF-Alpha;Tumor Necrosis Factor Ligand Superfamily Member 2;TNF-a;Tumor Necrosis Factor;Membrane Form;Tumor Necrosis Factor;Tnf;Tnfsf2;DIF;TNF-alpha;Tnfa;TNFalpha;Tnfsf1a;TNFSF2
UNIProt ID:
P06804

Documents