Elabscience

Recombinant Mouse PDGFRa/CD140a Protein (Fc Tag)

Product Code:
 
PKSM041120
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSM041120-10ug10ug£170.00
Quantity:
PKSM041120-50ug50ug£315.00
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Further Information

Abbreviation:
PDGFRa;CD140a
Accession:
P26618
Background:
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. PDGFRα and PDGFRβ are members of the class III RTK family. Inappropriate PDGFRα and PDGFRβ signaling has been linked to a number of proliferative disorders.
Calculated MW:
83.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
120-150 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu25-Glu524
Target Synonym:
Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A;Platelet-derived growth factor alpha receptor;CD140a;PDGFRA
UNIProt ID:
P26618

Documents