Elabscience

Recombinant Mouse NgR/RTN4R Protein (His Tag)

Product Code:
 
PKSM041117
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041117-10ug10ug£150.00
Quantity:
PKSM041117-50ug50ug£248.00
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Further Information

Abbreviation:
NgR;RTN4R
Accession:
Q99PI8
Background:
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
Calculated MW:
46.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
75-85 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Cys27-Ser447
Target Synonym:
Reticulon-4 Receptor;Nogo Receptor;NgR;Nogo-66 Receptor;RTN4R;NOGOR
UNIProt ID:
Q99PI8

Documents