Elabscience

Recombinant Mouse Interleukin-6/IL-6 Protein(His Tag)

Product Code:
 
PKSM041097
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSM041097-20ug20ug£210.00
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PKSM041097-100ug100ug£472.00
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Further Information

Abbreviation:
Interleukin-6;IL-6
Accession:
P08505
Activity:
Measure by its ability to induce proliferation in 7TD1 cells. The ED50 for this effectis < 0.01 ng/mL The specific activity of recombinant mouse IL-6 is approximately > 1x108 lU/mg.
Background:
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.
Calculated MW:
21.8 kDa
Endotoxin:
< 0.1 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from filtered solution of PBS,PH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
18 kDa
Purity:
> 98 % as determined by reducing SDS-PAGE.
Sequence:
Phe25-Thr211
Target Synonym:
Interleukin-6;IL-6;B-Cell Hybridoma Growth Factor;Interleukin HP-1;Il6;Il-6
UNIProt ID:
P08505

Documents