Elabscience

Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

Product Code:
 
PKSM041035
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041035-10ug10ug£256.00
Quantity:
PKSM041035-50ug50ug£553.00
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This product comes from: China.
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Further Information

Abbreviation:
Granzyme B;GZMB
Accession:
P04187
Background:
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Calculated MW:
26.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
35 kDa
Purity:
> 85 % as determined by reducing SDS-PAGE.
Sequence:
Gly19-Ser247
Target Synonym:
Granzyme B(G,H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1;Ctla1
UNIProt ID:
P04187

Documents