Elabscience

Recombinant Mouse CD32b/FCGR2B Protein (His Tag)

Product Code:
 
PKSM041016
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041016-10ug10ug£170.00
Quantity:
PKSM041016-50ug50ug£315.00
Quantity:
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Further Information

Abbreviation:
CD32b;FCGR2B
Accession:
P08101
Background:
Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
Calculated MW:
21.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
33 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Thr30-Pro210
Target Synonym:
Low affinity immunoglobulin gamma Fc region receptor II;Fc gamma receptor IIB;Fc-gamma RII;Fc-gamma-RIIB;FcRII;IgG Fc receptor II beta;Lymphocyte antigen 17;Ly-17;CD32;Fcgr2;Fcgr2b;Ly-17
UNIProt ID:
P08101

Documents