Elabscience

Recombinant Human HIP2/UBE2K Protein (His Tag, SUMO Tag)

Product Code:
 
PKSH033186
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PKSH033186-10ug10ug£226.00
Quantity:
PKSH033186-50ug50ug£283.00
Quantity:
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Further Information

Abbreviation:
HIP2;UBE2K
Accession:
P61086
Background:
Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain; with highest levels found in cortex and striatum; and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins; such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition; UBE2K is involved in Alzheimer's disease; Huntington's disease and antigen processing through its interaction with huntingtin; and MHC-heavy chain proteins.
Calculated MW:
34.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM PB;150mM NaCl;pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
38 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Asn200
Target Synonym:
Ubiquitin-Conjugating Enzyme E2 K;Huntingtin-Interacting Protein 2;HIP-2;Ubiquitin Carrier Protein;Ubiquitin-Conjugating Enzyme E2-25 kDa;Ubiquitin-Conjugating Enzyme E2(25K);Ubiquitin-Conjugating Enzyme E2-25K;Ubiquitin-Protein Ligase;UBE2K;HIP2;LIG
UNIProt ID:
P61086

Documents