Elabscience

Recombinant Human Transferrin Receptor/TFRC Protein (His Tag)(Active)

Product Code:
 
PKSH031302
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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CodeSizePrice
PKSH031302-100ug100ug£664.00
Quantity:
PKSH031302-1mg1mg£4,795.00
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Further Information

Abbreviation:
Transferrin Receptor;TFRC
Accession:
NP_003225.2
Activity:
Immobilized human CD71 at 10 ug/ml (100 ul/well) can bind human Transferrin. The EC50 of human Transferrin is 5. 6 ng/mL.
Background:
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
Calculated MW:
77.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
Purity:
> 85 % as determined by reducing SDS-PAGE.
Sequence:
Cys 89-Phe 760
Target Synonym:
Transferrin receptor protein 1;TR;TfR;Trfr;T9;p90;CD71;T9;TFR;TFR;TRFR

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