Elabscience

Recombinant Human SerpinA5/SERPINA5 Protein (His Tag)

Product Code:
 
PKSH033034
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PKSH033034-10ug10ug£219.00
Quantity:
PKSH033034-50ug50ug£497.00
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This product comes from: China.
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Further Information

Abbreviation:
SerpinA5;SERPINA5
Accession:
P05154
Background:
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes of blood of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to Serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
Calculated MW:
44.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
45 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
His20-Pro406
Target Synonym:
Plasma Serine Protease Inhibitor;Acrosomal Serine Protease Inhibitor;Plasminogen Activator Inhibitor 3;PAI-3;PAI3;Protein C Inhibitor;PCI;Serpin A5;SERPINA5;PCI;PLANH3;PROCI
UNIProt ID:
P05154

Documents