Elabscience

Recombinant Human SHMT1 Protein (His Tag)

Product Code:
 
PKSH033029
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PKSH033029-10ug10ug£219.00
Quantity:
PKSH033029-50ug50ug£497.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
SHMT1
Accession:
P34896
Background:
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.
Calculated MW:
53.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
55 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met3-Phe483
Target Synonym:
Serine Hydroxymethyltransferase Cytosolic;SHMT;Glycine Hydroxymethyltransferase;Serine Methylase;SHMT1
UNIProt ID:
P34896

Documents