Elabscience

Recombinant Human QPRT/QPRTase Protein (His Tag)

Product Code:
 
PKSH032985
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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PKSH032985-10ug10ug£256.00
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PKSH032985-50ug50ug£553.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
QPRT;QPRTase
Accession:
Q15274
Background:
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
Calculated MW:
33.0 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
34 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-His297
Target Synonym:
Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating];Quinolinate Phosphoribosyltransferase [Decarboxylating];QAPRTase;QPRTase;QPRT
UNIProt ID:
Q15274

Documents