Elabscience

Recombinant Human Proteinase 3/PRTN3 Protein (His Tag)

Product Code:
 
PKSH032974
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PKSH032974-10ug10ug£297.00
Quantity:
PKSH032974-50ug50ug£498.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Proteinase 3;PRTN3
Accession:
P24158
Background:
Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Calculated MW:
25.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 10mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
34 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala26-Arg249
Target Synonym:
Myeloblastin;AGP7;C-ANCA Antigen;Leukocyte Proteinase 3;PR-3;PR3;Neutrophil Proteinase 4;NP-4;P29;Wegener Autoantigen;PRTN3;MBN
UNIProt ID:
P24158

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