Elabscience

Recombinant Human PDGF-BB Protein (Active)

Product Code:
 
PKSH032906
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
1 / 1

No additional charges, what you see is what you pay! *

CodeSizePrice
PKSH032906-10ug10ug£219.00
Quantity:
PKSH032906-50ug50ug£497.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
PDGF-BB
Accession:
P01127
Activity:
Measured in a cell proliferation assay using BALB/C-3T3 cells. The ED50 for this effect is 15-60ng/ml.
Background:
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Calculated MW:
12.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 4mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
14 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser82-Thr190
Target Synonym:
Platelet-Derived Growth Factor Subunit B;PDGF Subunit B;PDGF-2;Platelet-Derived Growth Factor B Chain;Platelet-Derived Growth Factor Beta Polypeptide;Proto-Oncogene c-Sis;Becaplermin;PDGFB;PDGF2;SIS
UNIProt ID:
P01127

Documents