Elabscience

Recombinant Human Tau-D Protein (His Tag)

Product Code:
 
PKSH032757
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032757-10ug10ug£180.00
Quantity:
PKSH032757-50ug50ug£378.00
Quantity:
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Further Information

Abbreviation:
Tau-D
Accession:
P10636-6
Background:
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.
Calculated MW:
15.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
16 kDa
Purity:
> 85 % as determined by reducing SDS-PAGE.
Sequence:
Gln249-Gln381
Target Synonym:
Microtubule-Associated Protein Tau;Neurofibrillary Tangle Protein;Paired Helical Filament-Tau;PHF-Tau;MAPT;MAPTL;MTBT1;TAU
UNIProt ID:
P10636

Documents