Elabscience

Recombinant Human MASP1 Protein (His Tag)

Product Code:
 
PKSH032735
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032735-10ug10ug£256.00
Quantity:
PKSH032735-50ug50ug£553.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
MASP1
Accession:
P48740-2
Background:
Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
Calculated MW:
80.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris,200mM NaCl,10% Glycerol,pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
120 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
His20-Arg728
Target Synonym:
Mannan-Binding Lectin Serine Protease 1;Complement Factor MASP-3;Mannose-Binding Lectin-Associated Serine Protease 1;MASP-1;RaRF;Serine Protease 5;MASP1;CRARF;CRARF1;PRSS5
UNIProt ID:
P48740

Documents