Elabscience

Recombinant Human LDLR Protein (His Tag/AVI)

Product Code:
 
PKSH032711
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032711-20ug20ug£419.00
Quantity:
PKSH032711-100ug100ug£1,000.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
LDLR
Accession:
P01130
Background:
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Defects in LDLR will result in familial hypercholesterolemia.
Calculated MW:
90.1 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His-AVI
ObservedMW:
137 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala22-Arg788
Target Synonym:
Low-Density Lipoprotein Receptor;LDL Receptor;LDLR;FH;FHC;LDL R;LDL Receptor;LDLCQ2
UNIProt ID:
P01130

Documents