Elabscience

Recombinant Human HMGB1 Protein (MARI Tag)

Product Code:
 
PKSH032544
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032544-10ug10ug£180.00
Quantity:
PKSH032544-50ug50ug£378.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
HMGB1
Accession:
P09429
Background:
High mobility group protein B1 is a member of the HMGB family consisting of three members; HMGB1; HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein; HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile; it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte; T cell; dendritic cell activities in inflammatory responses.
Calculated MW:
10.0 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 50mM HEPES-Na;p H 7.9;500mM NaCl;0.6mM DTT.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-MARI
ObservedMW:
13 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Pro92-Val176
Target Synonym:
High Mobility Group Protein B1;High Mobility Group Protein 1;HMG-1;HMGB1;HMG1
UNIProt ID:
P09429

Documents