Elabscience

Recombinant Human ANGPTL8/β-trophin Protein (Fc Tag)

Product Code:
 
PKSH032067
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032067-10ug10ug£500.00
Quantity:
PKSH032067-50ug50ug£777.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
ANGPTL8;β-trophin
Accession:
Q6UXH0
Background:
The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.
Calculated MW:
46.0 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-Fc
ObservedMW:
54 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala22-Ala198
Target Synonym:
Betatrophin;Angiopoietin-like protein 8;Lipasin;Angptl8
UNIProt ID:
Q6UXH0

Documents