Elabscience

Recombinant Mouse Carbonic Anhydrase IX/CA9 Protein (His Tag)(Active)

Product Code:
 
PKSM040557
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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CodeSizePrice
PKSM040557-50ug50ug£493.00
Quantity:
PKSM040557-1mg1mg£4,606.00
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This product comes from: China.
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Further Information

Abbreviation:
Carbonic Anhydrase 9;CA9
Accession:
NP_647466.2
Activity:
Measured by its esterase activity. The specific activity is > 100 pmoles/min/ug.
Background:
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.
Calculated MW:
40.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
45-50 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Asp 390
Target Synonym:
RP23-195K8.9;CAIX;Ca9;MN/CA9

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