Elabscience

Recombinant Human IDH1 Protein (E.coli, His Tag)

Product Code:
 
PKSH030920
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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CodeSizePrice
PKSH030920-50ug50ug£889.00
Quantity:
PKSH030920-1mg1mg£5,378.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
IDH1
Accession:
O75874
Background:
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.
Calculated MW:
48 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 50mM Tris, 200mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
43 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Leu 414
Target Synonym:
Isocitrate Dehydrogenase [NADP] Cytoplasmic;IDH;Cytosolic NADP-Isocitrate Dehydrogenase;IDP;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;IDH1;PICD
UNIProt ID:
O75874

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