Elabscience

Recombinant Human CD3D & CD3E Heterodimer Protein (Active)

Product Code:
 
PKSH030479
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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CodeSizePrice
PKSH030479-50ug50ug£608.00
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PKSH030479-500ug500ug£2,872.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD3D & CD3E Heterodimer
Accession:
P04234-1&P07766-1
Activity:
Measured by its binding ability in a functional ELISA. Immobilized human CD3D & CD3E Heterodimer Protein at 10 ug/ml (100 ul/well) can bind OKT3-mIgG2a. The EC50 of OKT3-mIgG2a is 0.07-0.17 ug/ml.
Background:
T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Calculated MW:
77.5 (37.5+40) kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Flag & hFc
ObservedMW:
45-50 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ala105&Met 1-Asp126
Target Synonym:
T-Cell Surface Glycoprotein CD3 Delta Chain;T-Cell Receptor T3 Delta Chain;CD3d;CD3D;T3D
UNIProt ID:
P04234&P07766

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