Elabscience

HSD11B2 Polyclonal Antibody

Product Code:
 
E-AB-13311
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HSD11B2 Polyclonal Antibody at dilution 1:35
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Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using HSD11B2 Polyclonal Antibody at dilution 1:35
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HSD11B2 Polyclonal Antibody at dilution 1:35
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using HSD11B2 Polyclonal Antibody at dilution 1:35

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E-AB-13311-20uL20uL£125.00
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E-AB-13311-60uL60uL£172.00
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E-AB-13311-120uL120uL£237.00
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E-AB-13311-200uL200uL£344.00
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Further Information

Abbreviation:
HSD11B2
Background:
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human HSD11B2
Purification method:
Affinity purification
Target Synonym:
11 beta HSD2;11 beta hydroxysteroid dehydrogenase type 2;11 DH2;11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;11-DH2;AME;AME1;Corticosteroid 11 beta dehydrogenase isozyme 2;Corticosteroid 11-beta-dehydrogenase isozyme 2;DHI2;HSD11B2;HSD11K;HSD2;Hydroxysteroid 11 beta dehydrogenase 2;Hydroxysteroid 11 beta dehydrogenase isoenzyme 2;NAD dependent 11 beta hydroxysteroid dehydrogenase;NAD-dependent 11-beta-hydroxysteroid dehydrogenase;SDR9C3;Short chain dehydrogenase/reductase family 9C;member 3
UNIProt ID:
P80365

Documents