Elabscience

Cleaved-CASP4 p20 (Q81) Polyclonal Antibody

Product Code:
 
E-AB-30021
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Western Blot analysis of 3T3 cells using Cleaved-CASP4 p20 (Q81) Polyclonal Antibody at dilution of 1:2000.
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Western Blot analysis of 3T3 cells using Cleaved-CASP4 p20 (Q81) Polyclonal Antibody at dilution of 1:2000.

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E-AB-30021-20uL20uL£125.00
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E-AB-30021-60uL60uL£172.00
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E-AB-30021-120uL120uL£237.00
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E-AB-30021-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
Cleaved-Caspase-4 p20 (Q81)
Background:
This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
43kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the Internal region of human Caspase-4 p20
ObservedMW:
43+22kDa
Purification method:
Affinity purification
Target Synonym:
Apoptotic cysteine protease Mih1/TX;CASP-4;CASP4;CASP4;Caspase 4 apoptosis related cysteine peptidase;Caspase-4 subunit 2;Caspase4;ICE(rel)-II;ICE(rel)II;ICEREL II;ICH2;Mih1/TX;Protease ICH-2;Protease TX;TX
UNIProt ID:
P49662

Documents