Elabscience

CALR Polyclonal Antibody

Product Code:
 
E-AB-10352
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 3
Western Blot analysis of NIH/3T3 cell using CALR Polyclonal Antibody at dilution of 1:800
2 / 3
Immunohistochemistry of paraffin-embedded Human gastic cancer using CALR Polyclonal Antibody at dilution of 1:50
3 / 3
Immunohistochemistry of paraffin-embedded Human ovarian cancer using CALR Polyclonal Antibody at dilution of 1:50
❮❯

Western Blot analysis of NIH/3T3 cell using CALR Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human gastic cancer using CALR Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human ovarian cancer using CALR Polyclonal Antibody at dilution of 1:50

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-10352-20uL20uL£125.00
Quantity:
E-AB-10352-60uL60uL£172.00
Quantity:
E-AB-10352-120uL120uL£237.00
Quantity:
E-AB-10352-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Abbreviation:
CALR
Background:
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
48kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CALR
Purification method:
Affinity purification
Target Synonym:
Autoantigen RO;CALR;CALR protein;CALR;Calregulin;Calreticulin;cC1qR;CRP55;CRT;CRTC;Endoplasmic reticulum resident protein 60;Epididymis secretory sperm binding protein Li 99n;ERp60;FLJ26680;grp60;HACBP;HEL S 99n;RO;Sicca syndrome antigen A (autoantigen Ro;calreticulin);Sicca syndrome antigen A;SSA
UNIProt ID:
P27797

Documents

References

  • https://www.mdpi.com/2073-4409/9/12/2719
  • https://www.mdpi.com/1422-0067/19/12/3878