Elabscience

F7 Polyclonal Antibody

Product Code:
 
E-AB-91407
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using F7 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using F7 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-91407-60uL60uL£210.00
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E-AB-91407-120uL120uL£291.00
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E-AB-91407-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
F7
Background:
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
49kDa/51kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human F7
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
F7;SPCA
UNIProt ID:
P08709

Documents