Elabscience

α-Actinin-4 Polyclonal Antibody

Product Code:
 
E-AB-91500
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using α-Actinin-4 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using α-Actinin-4 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-91500-60uL60uL£210.00
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E-AB-91500-120uL120uL£291.00
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E-AB-91500-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
α-Actinin-4
Background:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
59kDa/79kDa/104kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human α-Actinin-4
ObservedMW:
105kDa
Purification method:
Affinity purification
Target Synonym:
ACTN4;ACTININ-4;FSGS;FSGS1
UNIProt ID:
O43707

Documents