Elabscience

SELENOK Polyclonal Antibody

Product Code:
 
E-AB-92295
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using SELENOK Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using SELENOK Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92295-60uL60uL£210.00
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E-AB-92295-120uL120uL£291.00
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E-AB-92295-200uL200uL£431.00
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Further Information

Abbreviation:
SELENOK
Background:
The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Pseudogenes of this locus have been identified on chromosomes 6 and 19.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
10kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human SELENOK
ObservedMW:
11KDa
Purification method:
Affinity purification
Target Synonym:
SELK; HSPC030; HSPC297
UNIProt ID:
Q9Y6D0

Documents