Elabscience

E-Cadherin Polyclonal Antibody

Product Code:
 
E-AB-93060
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
1 / 2
Immunohistochemistry of paraffin-embedded Rat kidney using E-Cadherin Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
2 / 2
Immunofluorescence analysis of MCF7 cells using E-Cadherin Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
❮❯

Immunohistochemistry of paraffin-embedded Rat kidney using E-Cadherin Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunofluorescence analysis of MCF7 cells using E-Cadherin Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-93060-60uL60uL£210.00
Quantity:
E-AB-93060-120uL120uL£291.00
Quantity:
E-AB-93060-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
E-Cadherin
Background:
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
90kDa/97kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:100,IF 1:50-1:200
Immunogen:
A synthetic peptide of human E-Cadherin
ObservedMW:
125KDa
Purification method:
Affinity purification
Target Synonym:
Arc-1;CD324;CDHE;ECAD;LCAM;UVO;CDH1;E-Cadherin
UNIProt ID:
P12830

Documents