Elabscience

Recombinant Human P21 protein (His tag)

Product Code:
 
PDEH100242
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PDEH100242-20ug20ug£113.00
Quantity:
PDEH100242-100ug100ug£140.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
P21
Accession:
P38936
Background:
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Calculated MW:
13.64 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
18 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gly 40-Pro 164
Target Synonym:
CAP20;CDK-interacting protein 1;CDKI;CDKN1;CDN1A;CIP1;CDKN1A;Cyclin Dependent Kinase Inhibitor 1A;DNA Synthesis Inhibitor;MDA-6;MDA6;Melanoma differentiation-associated protein 6;P21cip1;P21waf;PIC1;SDI1;SLC12A9;WAF1
UNIProt ID:
P38936

Documents