Elabscience

Recombinant Human Calnexin/CANX protein (His tag)

Product Code:
 
PDEH100247
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PDEH100247-20ug20ug£113.00
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PDEH100247-100ug100ug£140.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Calnexin;CANX
Accession:
P27824
Background:
Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
Calculated MW:
25.3 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-10His
ObservedMW:
42 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
His 21-Leu 251
Target Synonym:
Calnexin;IP90;Major Histocompatibility Complex Class I Antigen-Binding Protein p88;p90;CANX
UNIProt ID:
P27824

Documents