Elabscience

Recombinant Human P-glycoprotein1/ABCB1 protein (His tag)

Product Code:
 
PDEH100361
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDEH100361-20ug20ug£113.00
Quantity:
PDEH100361-100ug100ug£140.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
P-glycoprotein1;ABCB1
Accession:
P08183
Background:
Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218, PubMed:35970996). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218, PubMed:35970996).
Calculated MW:
25.96 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
32 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu 392-Met 628
Target Synonym:
ATP-dependent translocase ABCB1;ABCB1;ATP-binding cassette sub-family B member 1;P-glycoprotein 1;Phospholipid transporter ABCB1;CD243;
UNIProt ID:
P08183

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