Elabscience

Recombinant Mouse CASP1 protein (His tag)

Product Code:
 
PDEM100052
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDEM100052-20ug20ug£113.00
Quantity:
PDEM100052-100ug100ug£140.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CASP1
Accession:
P29452
Background:
Caspase-1, also known as IL-1 beta -converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa (aa 120-297) and two 10 kDa (aa 317-404) subunits which associate following cleavage of inactive precursors. Caspase-1 is required for proteolytic cleavage of the IL-1 beta precursor to form the active proinflammatory cytokine. Alternate splicing generates several additional Caspase-1 isoforms with deletions in the propeptide regions or also in the mature subunits.
Calculated MW:
19.36 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
21 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asn 120-Asp 296
Target Synonym:
CASP-1;CASP1;CASP1;Caspase 1;Caspase-1 subunit p10;ICE;IL-1 beta-converting enzyme;IL-1BC
UNIProt ID:
P29452

Documents