Elabscience

Recombinant Human B7-H3/CD276 Protein (His Tag)

Product Code:
 
PDMH100007
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDMH100007-20ug20ug£178.00
Quantity:
PDMH100007-100ug100ug£237.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
B7-H3;CD276
Accession:
Q5ZPR3
Background:
CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20?27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
Calculated MW:
47.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
60-80 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu29-Thr461
Target Synonym:
CD276;B7H34Ig-B7-H3;B7-H3;B7 homolog 3;CD276 antigen;CD276 molecule;Costimulatory molecule
UNIProt ID:
Q5ZPR3

Documents