Elabscience

Recombinant Rat Interleukin-12 subunit beta/IL-12B protein (His tag)

Product Code:
 
PDMR100029
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDMR100029-20ug20ug£269.00
Quantity:
PDMR100029-100ug100ug£397.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
IL-12B
Accession:
E9PU71
Background:
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Calculated MW:
36.74 kDa
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
42 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Ser335
Target Synonym:
Interleukin-12 subunit beta;Cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p40;Il12b;rCG_35081
UNIProt ID:
E9PU71

Documents