Elabscience

Recombinant Human TLK1/PKU-beta Protein (His & GST Tag)(Active)

Product Code:
 
PKSH030339
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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PKSH030339-50ug50ug£652.00
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Further Information

Abbreviation:
TLK1;PKU-beta
Accession:
Q9UKI8-1
Activity:
The specific activity was determined to be 1. 6 nmol/min/mg using Histone H3 protein as substrate.
Background:
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Calculated MW:
114 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
Baculovirus-Insect Cells
Formulation:
Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His & GST
ObservedMW:
125 kDa
Purity:
> 88 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Tyr 766
Target Synonym:
KIAA0137;PKU-beta
UNIProt ID:
Q9UKI8

Documents