Elabscience

Recombinant Human TXNRD1/TRXR1 Protein (aa 161-647, His Tag)

Product Code:
 
PKSH030732
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
TXNRD1;TRXR1
Accession:
Q16881-1
Background:
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.
Calculated MW:
55 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
60 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Tyr 161-Cys 647
Target Synonym:
GRIM-12;TR;TR1;TRXR1;TXNR
UNIProt ID:
Q16881

Documents