Elabscience

Recombinant Human CD8 beta/CD8B Protein (Fc Tag)

Product Code:
 
PKSH031296
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD8 beta;CD8B
Accession:
P10966-1
Background:
CD8B (CD8b molecule); also known as P37 and LEU2; contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen; acting as a coreceptor; and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains; or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene; also located on chromosome 2; has been identified. CD8 is thought to play a role in the process of T-cell mediated killing.
Calculated MW:
44 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-hFc
ObservedMW:
50 kDa
Purity:
> 93 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Pro 170
Target Synonym:
T-Cell Surface Glycoprotein CD8 Beta Chain;CD8b;CD8B;CD8B1;LEU2;LY3;LYT3;P37
UNIProt ID:
P10966

Documents