Elabscience

Recombinant Human Troponin C/TNNC1 Protein

Product Code:
 
PKSH031309
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH031309-100ug100ug£763.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Troponin C;TNNC1
Accession:
NP_003271.1
Background:
Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Calculated MW:
18.4 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
20 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Glu161
Target Synonym:
CMD1Z;CMH13;TN-C;TNC;TNNC

Documents