Elabscience

Recombinant Human Kallikrein 13/KLK13 Protein (His Tag)(Active)

Product Code:
 
PKSH031770
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH031770-50ug50ug£773.00
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This product comes from: China.
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Further Information

Abbreviation:
Kallikrein 13;KLK13
Accession:
NP_056411.1
Activity:
Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (R&D Systems, Catalog # ES011). The specific activity is > 200 pmoles/min/ug. (Activation description: The proenzyme needs to be activated by Lysyl-Endopeptidase for an activated form)
Background:
Tissue kallikrein 13 (hK13); also known as KLK-L4 (kallikrein-like gene 4); is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like; secreted serine protease expressed specifically in the testicular tissue including prostate; salivary gland; breast; and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers; and is regarded as a novel cancer biomarker. In addition; KLK13 interacts and forms complexes with several serum protease inhibitors; such as alpha2-macroglobulin; and its expression is regulated by steroid hormones.
Calculated MW:
28.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ile 262
Target Synonym:
Kallikrein-13;Kallikrein-Like Protein 4;KLK-L4;KLK13;KLKL4

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