Elabscience

Recombinant Human KIM-1(C-6His)

Product Code:
 
PKSH033813
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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PKSH033813-1mg1mg£1,024.00
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Further Information

Abbreviation:
KIM-1
Accession:
F1CME6
Background:
Kidney injury molecule-1 (KIM-1) (also known as TIM-1 and HAVCR) is a type 1 transmembrane glycoprotein found on activated CD4+ T cells, especially Th2 cells, and dedifferentiated proximal tubule epithelial cells. In humans, KIM-1 levels are very low or undetectable in normal samples, but following drug toxicity or ischemic damage to the kidney, the 85 kD, mucin-rich extracellular region of this molecule is shed and detected at elevated levels in urine, serum, and plasma. Therefore, KIM-1 is a suitable renal biomarker capable of early detection and progressive monitoring of acute kidney injury beyond traditional injury markers such as serum creatinine (SCr) and blood urea nitrogen (BUN) which lack specificity and sensitivity. KIM-1 has also been implicated in the development of atopic airway disease (asthma) and Th2-biased autoimmune responses.
Calculated MW:
29.8 kDa
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 uM filtered solution of PBS,pH7.4,5% Trehalose
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
80-120 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser21-Gly290
Target Synonym:
HAVCR1;HAVCR;HAVCR-1;KIM-1;KIM1;TIM;TIM-1;TIM1;TIMD-1;TIMD1;Hepatitis A virus cellular receptor 1
UNIProt ID:
F1CME6

Documents