Elabscience

Recombinant Mouse CD112/Nectin-2 Protein (His Tag)(Active)

Product Code:
 
PKSM040739
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSM040739-100ug100ug£664.00
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Further Information

Abbreviation:
CD112;Nectin-2
Accession:
NP_033016.3
Activity:
1. Immobilized mouse CD112-His at 10 ug/ml (100 ul/well) can bind biotinylated mouse DNAM1-His with a linear range of 0.156-5.0 ug/ml. 2. Immobilized mouse CD112-His at 10 ug/ml (100 ul/well) can bind mouse DNAM1-Fc with a linear range of 0.03-1.0 ug/ml.
Background:
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
Calculated MW:
36 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
40-45 kDa
Purity:
> 98 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Gly 351
Target Synonym:
AI325026 Protein;AI987993 Protein;Cd112 Protein;MPH Protein;nectin-2 Protein;Pvr Protein;Pvs Protein

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