Elabscience

Recombinant Rat BTLA/CD272 Protein (ECD, Fc Tag)(Active)

Product Code:
 
PKSR030140
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Rat
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSR030140-100ug100ug£664.00
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This product comes from: China.
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Further Information

Abbreviation:
BTLA;CD272
Accession:
NP_998795.1
Activity:
Immobilized rat BTLA-mFc at 10 ug/mL (100 uL/well) can bind mouse HVEM-Fch. The EC50 of mouse EFNA5-Fc is 6. 2-14.4 ng/mL.
Background:
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).
Calculated MW:
43.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-mFc
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala6-Tyr183
Target Synonym:
BTLA

Documents