Elabscience

Recombinant Rat EGFR/ErbB1 Protein (His Tag)(Active)

Product Code:
 
PKSR030363
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Rat
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSR030363-100ug100ug£664.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
EGFR;ErbB1
Accession:
E7CXR8
Activity:
Measured by its ability to bind recombinant human EGF-Fc and mouse EGF-Fc in functional ELISA.
Background:
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
Calculated MW:
70.7 kDa
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
93-110 kDa
Purity:
> 98 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Ser646
Target Synonym:
EGFR
UNIProt ID:
E7CXR8

Documents