NSJ Bioreagents

CD31 Antibody / PECAM-1

Product Code:
 
NSJ-V8788SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
r6439
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Aliquot the CD31 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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SDS-PAGE analysis of purified, BSA-free CD31 antibody (r6439) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free CD31 antibody (r6439) as confirmation of integrity and purity.

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CodeSizePrice
NSJ-V8788SAF-100UG100ug£534.00
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Further Information

Application Details:
Flow cytometry: 0.5-1ug/million cells,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the CD31 antibody should be determined by the researcher.
Description:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A portion of amino acids 28-330 was used as the immunogen for the CD31 antibody.
Limitation:
This CD31 antibody is available for research use only.
Localization:
Cell surface and cytoplasm of endothelial cells
Purity:
Protein A/G affinity
Uniprot #:
P16284

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