NSJ Bioreagents

UACA Antibody

Product Code:
 
NSJ-V2797SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
UACA/1222
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store the UACA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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Western blot of A549 cell lysate using UACA antibody (UACA/1222)
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Western blot of A549 cell lysate using UACA antibody (UACA/1222)

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NSJ-V2797SAF-100UG100 ug£534.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the UACA antibody should be determined by the researcher.
Description:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant human protein was used as the immunogen for the UACA antibody.
Limitation:
This UACA antibody is available for research use only.
Localization:
Nuclear membrane
Purity:
Protein G affinity chromatography
Uniprot #:
Q9BZF9

Documents