Bcl10 Antibody

Product Code:

NSJ-V9102SAF

Product Group:

Primary Antibodies

Supplier:

NSJ Bioreagents

Host Type:

Mouse

Antibody Isotype:

Mouse IgG1 kappa

Antibody Clonality:

Monoclonal

Antibody Clone:

SPM520

Regulatory Status:

RUO

Target Species:

Human

Application:

Immunohistochemistry- Paraffin Embedded (IHC-P)

Storage:

Store the Bcl10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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Code	Size	Price

NSJ-V9102SAF-100UG

100 ug

£534.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Application Details:

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1) (2)

Application Note:

Optimal dilution of the antibody should be determined by the researcher.

Description:

Bcl10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of Bcl10 was shown to induce NF-kB activation in a NIK-dependent pathway. This mAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

Format:

Purified

Formulation:

1 mg/ml in 1X PBS; BSA free, sodium azide free

Immunogen:

Amino acids 122-168 were used as the immunogen for this Bcl10 antibody.

Limitation:

This Bcl10 antibody is available for research use only.

Localization:

Nuclear and cytoplasmic

Purity:

Protein G affinity chromatography

Uniprot #:

O95999

Documents

Datasheet