NSJ Bioreagents

MCM7 Antibody

Product Code:
 
NSJ-V3501IHC
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MCM7/1467
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the MCM7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 2
IHC testing of FFPE human tonsil with MCM7 antibody (clone MCM7/1467). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.~
2 / 2
SDS-PAGE Analysis of Purified, BSA-Free MCM7 Antibody (clone MCM7/1467). Confirmat

IHC testing of FFPE human tonsil with MCM7 antibody (clone MCM7/1467). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.~
SDS-PAGE Analysis of Purified, BSA-Free MCM7 Antibody (clone MCM7/1467). Confirmat

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NSJ-V3501IHC-7ML7 ml£534.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Application Note:
Titering of the MCM7 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Description:
MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Format:
Purified
Formulation:
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Immunogen:
A human partial recombinant protein corresponding to amino acids 195-319 was used as the immunogen for the MCM7 antibody.
Limitation:
This MCM7 antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein G affinity chromatography
Uniprot #:
P33993

Documents