ELK Biotechnology

Recombinant K. pneumoniae NEO

Product Code:
 
ELK-EPT008
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Bacteria
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped on dry ice/polar packs.
Storage:
 
Store at -70°C, stable for 6 months after receipt. Store at -70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
ELK-EPT008-50ug50ug£573.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
P00552
Alternative Names:
Aminoglycoside 3'-phosphotransferase; APH(3')-II; APH(3')II; Kanamycin kinase type II; Neomycin-kanamycin phosphotransferase type II; neo
Apparent Molecular Weight:
26-30 KDa, reducing conditions
Background:
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Molecular Weight:
29 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.