ELK Biotechnology

Recombinant Human IL-7

Product Code:
 
ELK-EPT013
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature.
Storage:
 
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
ELK-EPT013-50ug50ug£741.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
P13232
Alternative Names:
Interleukin-7; IL-7; IL7
Apparent Molecular Weight:
18 KDa, reducing conditions
Background:
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
Biological Activity:
Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.02-0.08 ng/ml.
Endotoxin:
Less than 0.001 ng/ug (0.01 EU/ug) as determined by LAL test.
Molecular Weight:
17.5 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Redissolve:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.?