ELK Biotechnology

Recombinant Cynomolgus 4-1BB (C-Fc)

Product Code:
 
ELK-EPT062
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Monkey
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature.
Storage:
 
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
ELK-EPT062-50ug50ug£348.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
A9YYE7
Alternative Names:
CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA
Apparent Molecular Weight:
60 KDa, reducing conditions
Background:
Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).
Biological Activity:
Immobilized Cynomolgus 4-1BB-Fc(Cat#CB19) at 2ug/ml (100 ul/well)can bind Human 4-1BBL-His-Flag(Cat#C17A). The ED50 of Human 4-1BBL-His-Flag(Cat#C17A)is 0.418 ug/ml.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Molecular Weight:
44.4 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Redissolve:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.?